Project ELDORADO

Brazil Cameroun France Ivory Coast Mozambique Thailand

Project ongoing

clinicaltrials.gov

Short description

Evaluation of treatment with Doravirin as an alternative to Dolutegravir in antiretroviral treatment-naïve people living with HIV-1

Domains

  • Research

Themes

  • Communicable diseases

Sub-themes

  • VIH, VIH-1

Countries

  • Brazil
  • Cameroun
  • France
  • Ivory Coast
  • Mozambique
  • Thailand

Participating teams in Bordeaux

GHiGS team at the BPH

Partner institutions in France

ANRS
Association Nationale de Réadaptation Sociale
 Adera APHP Inserm Institut de Recherche pour le Développement (IRD) CHU Bordeaux CHU Nantes CHU Montpellier

International partner institutions

INI Fiocruz (BR) Hopital General Nova Iguaçu (BR)
Hôpital Central de Yaoundé (CM)
 Site ANRS du Cameroun (CM) Programme PaC-CI  (Côte d’Ivoire)
Laboratoire de virologie et bactériologie du CHU de Treichville
 CNTS (CI)
 CEPREF (CI)
CISPOC (MZ)
Centro de Saude 1ro De Mai (MZ)
Chiang Mai University (TH)

Donors

ANRS
Association Nationale de Réadaptation Sociale
 Global Health EDCTP3
European Union

Activity summary

Phase III, multicentre, open-label, randomised, non-inferiority clinical trial designed to assess the non-inferiority of doravirine in combination with tenofovir and lamivudine, compared with dolutegravir in combination with tenofovir and lamivudine or emtricitabine, in treatment-naive people living with HIV-1.

Project contact

Anthony L’Hostellier
anthony.lhostellier@u-bordeaux.fr

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